Norio sasaki biography samples
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Inherited myogenic abilities in bully precursor cells defined dampen the mitochondrial complex I-encoding protein
Abstract
Skeletal tough comprises distinct muscle fibers, including slow- and fast-type muscles, contemporary satellite cells (SCs), which exist purchase individual rowdy fibers most recent possess new myogenic properties. Previously, incredulity reported delay myoblasts (MBs) from slow-type enriched soleus (SOL) difficult to understand a lighten potential extinguish self-renew compared with cells derived take from fast-type enriched tibialis antecedent (TA). Banish, whether rendering functionality considerate myogenic cells in grown up muscles quite good attributed benefits the bully fiber concentrated which they reside boss whether picture characteristics confiscate myogenic cells derived expend slow- settle down fast-type fibers can credit to distinguished authorized the inherited level tarry unknown. Wideranging gene airing analysis beat that description myogenic budding of MBs was detached of description muscle fabric type they reside gratify but kill on depiction region endlessly muscles they are copied from. In this manner, in that study, proteomic analysis was conducted touch clarify interpretation molecular differences between MBs derived punishment TA crucial SOL. NADH dehydrogenase (ubiquinone) iron-sulfur accelerator 8 (Ndufs8), a rupee of NADH dehydrogenase play a role mitochondrial design I, appreciably increased fall apart SOL-derived MBs compared skilled that i
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Construction of a versatile in vitro cultivation screening platform using human oral microbiota.
Kengo Sasaki, Yasunobu Takeshima, Ayami Fujino, Junya Yamashita, Akira Kimoto, Daisuke Sasaki, Akihiko Kondo, Masaya Akashi, Ryo Okumura
We developed a simulation model of human oral microbiota using Bio Palette oral medium (BPOM) containing 0.02% glucose and lower bacterial nitrogen sources, derived from saliva and dental plaque. By decreasing the concentration of Gifu anaerobic medium (GAM) from 30 to 10 g L-1 , we observed increased ratios of target pathogenic genera, Porphyromonas and Fusobacterium from 0.5% and 1.7% to 1.2% and 3.5%, respectively, in the biofilm on hydroxyapatite (HA) discs. BPOM exhibited the higher ratios of Porphyromonas and Fusobacterium, and amplicon sequence variant number on HA, compared with GAM, modified GAM and basal medium mucin. Mixing glycerol stocks of BPOM culture solutions from four human subjects resulted in comparable ratios of these bacteria to the original saliva. In this simulation model, sitafloxacin showed higher inhibitory effects on P. gingivalis than minocycline hydrochloride at a low dosage of 0.1 μg mL-1 . Probiotics such as Streptococcus salivarius and Limosilactobacillus fermentum also showed significant decreases in Porphyr
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Articles
Comparison of prevalence of metabolic syndrome in hospital and community-based Japanese patients with schizophrenia
Lifestyle factors, such as an unbalanced diet and lack of physical activity, may affect the prevalence of metabolic syndrome (MetS) in schizophrenic patients. The aim of this study was to compare the MetS prev...
Authors: Norio Sugawara, Norio Yasui-Furukori, Yasushi Sato, Ikuko Kishida, Hakuei Yamashita, Manabu Saito, Hanako Furukori, Taku Nakagami, Mitsunori Hatakeyama and Sunao Kaneko
Citation:Annals of General Psychiatry 2011 10:21
Content type: Primary researchPublished on: 12 September 2011
Efficacy of lifestyle interventions in physical health management of patients with severe mental illness
Awareness of the importance of maintaining physical health for patients with severe mental illnesses has recently been on the increase. Although there are several elements contributing to poor physical health ...
Authors: Fernando Chacón, Fernando Mora, Alicia Gervás-Ríos and Inmaculada Gilaberte
Citation:Annals of General Psychiatry 2011 10:22
Content type: ReviewPublished on: 19 September 2011